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Útgefið gæðaskjal: Leiðbeiningar
Skjalnúmer: Rklín-344
Útg.dags.: 12/06/2022
Útgáfa: 3.0
2.02.03.02.01 Aminolevulinat

Pt(U)-Aminolevulinat, dALA, Pt(U)-5-Aminolevulinate, DALA,delta Aminolevulinat, U-5-ALA, 5-Aminolevulinat.Aminolävulinsäure, 5-amino-4-Oxovaleric acid, amino-Levulinic acid, Kerastick

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Gerð sýnis: Sólarhringsþvag. Ekki bæta við sýru né basa í þvagið

Muna að skrá magn sólarhringsþvags.

Magn: 20 mL vel blandað sólarhringsþvag (minnst 10 mL)
Geymsla sýnis: Söfnunin skal geymd í kulda og myrkri, ekki frysta
Sýnasending: Hraðsending til útlanda.
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MVZ Labor PD Dr. Volkmann und Kollegen GbR
Kriegsstrasse 99
76133 Karlsruhe

Tel:  0721 85000-0
Fax: 0721 85000-199

www.laborvolkmann.de
E-Mail: labor@laborvolkmann.de

Einnig mælt á Rigshospitalet: http://labportal.rh.dk/LabPortal.asp?Mode=View&Id=2934 og Karolinska: Aminolevulinsyra Karolinska.pdfAminolevulinsyra Karolinska.pdf
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5-aminolaevulinsaeure.pdf5-aminolaevulinsaeure.pdf

http://www.laborvolkmann.de/analysenspektrum/HTML/index.html

Fróðleikur: 5-Aminolevulinic acid is a compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. Aminolevulinic Acid is a topically administered metabolic precursor of protoporphyrin IX. After topical administration, aminolevulinic acid (ALA) is converted to protoporphyrin IX (PpIX) which is a photosensitizer. Increased ALA concentration is associated with exposure to alcohol, lead, and a variety of other agents.  Massive elevation of ALA occurs in the acute porphyrias and hereditary tyrosinemia.
Specimen preservation with acid or base is discouraged and may cause assay interference.  When collecting urine for additional tests that require acid or base preservation, the ALA aliquot should be removed prior to the addition of the acid or base.

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Ingibjörg Loftsdóttir
Sigrún H Pétursdóttir
Guðmundur Sigþórsson
Kristín Sigurgeirsdóttir

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Ísleifur Ólafsson

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