Samheiti: AFP-AF í legvatni, Alpha-Fetoprotein í legvatni, Amn- , Amn-Alfa-Fetoprotein
Sýnataka, geymsla og sýnasending
Gerđ sýnis: Legvatn (Amniotic fluid)
Forđist ađ sýniđ blandist blóđi fóstursins.
Geymsla sýnis: Kćlir.
Sýnasending: Hrađsending í umhverfishita.
Fetoprotein, alfa-, Amn.pdf
Fróđleikur: There are two categories of AFP tests: tests performed on serum (blood plasma), and tests performed on amniotic fluid. Tests performed on serum are further categorized by the reason for performing the test: maternal serum, adult tumor marker, and pediatric tumor markerThe level of placental alpha-fetoprotein (AFP) in normal pregnancy at term was found to be 5050 +/- ng/g fresh tissue. A significant increase was noted in the toxemic placenta associated with a rise in circulating maternal AFP level and a nonsignificant increase in cord blood. AFP in amniotic fluid has one or two sources. The fetus normally excretes AFP into its urine, hence into the amniotic fluid. A fetus with one of three broad categories of defects also releases AFP by other means. These categories are open neural tube defect, open abdominal wall defect, and skin disease or other failure of the interior or exterior body surface.
Abnormally elevated AFP in amniotic fluid can have one or more of many different causes:
- normal elevation. 75% of AF AFP test results in the range 2.0 to 4.9 MoM are false positives: the baby is normal.
- open neural tube defect
- open abdominal wall defect
- congenital nephrosis