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Útgefiđ gćđaskjal: Leiđbeiningar
Skjalnúmer: Rklín-641
Útg.dags.: 09/16/2020
Útgáfa: 1.0
2.02.03.02.01 Fibroblast growth factor 23 (FGF23)

Samheiti: FGF23
Hide details for Sýnataka, geymsla og sýnasending Sýnataka, geymsla og sýnasending
Gerđ sýnis : EDTA-plasma. Sýni ţarf ađ snúa niđur innan 8 tíma frá blóđtöku.
Sýni tekiđ í glas međ fjólubláum tappa án gels (svört miđja) . Litakóđi samkvćmt GREINER.


Magn: 1 ml plasma
Geymsla sýnis: Frystir
Sýnasending: Hrađsending á ţurrís
Hide details for Heiti tilvísunarannsóknastofu og heimilisfangHeiti tilvísunarannsóknastofu og heimilisfang
Klinisk Biokemisk Afdeling
Rigshospitalet, Glostrup
Valdemar Hansens Vej 13, indgang 3, VB 2.sal, 2600 Glostrup
Tlf.: 38 63 24 76 Fax: 38 63 39 58

Netfang: helle.hedegaard.lethmar@regionh.dk
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FGF23.pdfFGF23.pdf

Fróđleikur: The FGF23 gene provides instructions for making a protein called fibroblast growth factor 23, which is produced in bone cells. This protein is necessary in regulating the phosphate levels within the body (phosphate homeostasis). Among its many functions, phosphate plays a critical role in the formation and growth of bones in childhood and helps maintain bone strength in adults. Phosphate levels are controlled in large part by the kidneys. The kidneys normally rid the body of excess phosphate by excreting it in urine, and they reabsorb this mineral into the bloodstream when more is needed. Fibroblast growth factor 23 signals the kidneys to stop reabsorbing phosphate into the bloodstream.


How Fibroblast Growth Factor 23 Works | American Society of Nephrology



Pathogenesis of disordered mineral metabolism in CKD. (a) Traditional view of the mechanisms that maintain secondary hyperparathyroidism in advanced chronic kidney disease. (b) Updated view of the mechanisms that initiate secondary hyperparathyroidism in chronic kidney disease, emphasizing the central role of FGF23. CaR, calcium sensing receptor; FGFR, fibroblast growth factor receptor; PTH, parathyroid hormone; VDR, vitamin D receptor.

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Ritstjórn

Kristín Sigurgeirsdóttir
Sigrún H Pétursdóttir
Guđmundur Sigţórsson
Ingibjörg Loftsdóttir

Samţykkjendur

Ábyrgđarmađur

Ísleifur Ólafsson

Útgefandi

Sigrún H Pétursdóttir

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