Minimum 10 mL urine required
Store frozen unless sent immediately
Fróðleikur:
Sulphonylurea Screen (Sulfonylurea Screen)
General Information
The sulphonylureas act mainly by augmenting insulin secretion and consequently are effective only when some residual pancreatic beta-cell activity is present; during; long-term administration they also have an extra-pancreatic action. All may lead to hypoglycaemia 4 hours or more after food but this is usually an indication of overdose, and is relatively uncommon.
The qualitative analysis of plasma or urine for the presence of sulphonylurea drugs is a specific investigation and is performed when requested or when the drug history of the patient indicates the possibility of sulphonylurea ingestion.
The follow compounds can be detected using this method:
- Chlorpropamide
- Glibenclamide
- Gliclazide
- Glimepiride
- Glipizide
- Tolbutamide.
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