Samheiti: Chylomicron, Lipoproteinelektrophorese
Sřnataka, geymsla og sřnasending
Sj˙klingur ■arf a vera fastandi 12 tÝma fyrir blˇt÷ku.
Ger sřnis : Serum
Sřni teki Ý serum glas me rauum tappa me geli (gul mija) ea me rauum tappa ßn gels (sv÷rt mija)
. Litakˇi samkvŠmt Greiner.
Geymsla sřnis: KŠlir. EKKI frysta sřni. Sřni geymist 10 daga Ý kŠli
Sřnasending: Hrasending Ý stofuhita
Lipoprotein elektrophoresis i.s.░. (HDL, LDL, VLDL, Chylomikronen)
comments12 h fasting before blood draw
stability RT 3 days
4-8░C 10 days
do not freeze
TAT 10 working days
áFrˇleikur: Chylomicron: A small fat globule composed of protein and lipid (fat). Chylomicrons are found in the blood and lymphatic fluid where they serve to transport fat from its port of entry in the intestine to the liver and to adipose (fat) tissue. After a fatty meal, the blood is so full of chylomicrons that it looks milky
Chylomicron retention disease:
Chylomicron retention disease is a rare, hereditary, autosomal recessive disorder that affects the absorption of dietary lipids, cholesterol and certain fat-soluble vitamins, A,D,E and K due to a lack of chylomicron transportation. Mutations in the SAR1Bgene impair the release of chylomicrons into the blood stream.
The signs and symptoms of chylomicron retention disease appear in the first few months of life and they include:
Failure of weight-gain and growth
Steatorrhea (fatty stools)
Hypocholesterolemia (low blood cholesterol)
Later in life:
Impaired nervous system
Decreased reflexes (hypoflexia)
Decreased ability to feel vibrations
Chylomicron electrophoresis for confirmation and quantification.