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Útgefiđ gćđaskjal: Leiđbeiningar
Skjalnúmer: Rklín-523
Útg.dags.: 01/08/2020
Útgáfa: 2.0
2.02.03.02.01 Amphotericin

Samheiti: Amphotericinum B, Liposomal amphotericin B
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Gerđ sýnis : Serum / plasma

Verja sýni fyrir ljósi, álpappír

Sýni tekiđ í serum glas međ rauđum tappa međ geli (gul miđja) eđa međ rauđum tappa án gels (svört miđja)
Einnig má taka sýni í glas međ fjólubláum tappa án gels (svört miđja)


Magn: 1ml (min 0,3ml)
Geymsla sýnis: Frystir
Sýnasending: Hrađsending á ţurrís
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ANNAĐUT
Beiđni:Drogenanalytik Labor Bremen.pdfDrogenanalytik Labor Bremen.pdf Svar kemur í FAX

Mćling kostar 7346 kr (24.09.19)
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Medizinisches Labor Bremen
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D-28357 Bremen

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Netföng: info@mlhb.de
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Amphotericin B
    • Analysen
      Analysengruppen
      Antibiotika-Konzentrationen, Antimykotika
      Präanalytik
      Stabilität: 14 Tage bei - 70 °C
Probenmaterial
Serum/ Plasma
Menge (optimal)
0,3 mL
Häufigkeit
nach Bedarf
Präanalytik
Lichtgeschützt (Röhrchen mit Alufolie umwickeln).
Methode
LC-MS
Referenzbereich / Entscheidungsgrenze
Wert
Talspiegel0,02 - 1,0 mg/L
Gipfelspiegel1,5 - 3,5 mg/L
Tox. Ber.> 5,0 mg/L

Letzte Änderungen: 02.10.2015

Fróđleikur:
Amphotericin B is a polyene antifungal antibiotic produced by Streptomyces nodosus, with antifungal activity. Amphotericin B binds to ergosterol, an essential component of the fungal cell membrane, thereby causing depolarization of the membrane and altering cell membrane permeability. This leads to leakage of important intracellular components, cell rupture, and eventually cell death. This agent may also induce oxidative damage in fungal cells and has been reported to stimulate host immune cells.


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    Ingibjörg Loftsdóttir
    Sigrún H Pétursdóttir
    Guđmundur Sigţórsson
    Kristín Sigurgeirsdóttir

    Samţykkjendur

    Ábyrgđarmađur

    Ísleifur Ólafsson

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