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┌tgefi­ gŠ­askjal: Lei­beiningar
Skjaln˙mer: RklÝn-494
┌tg.dags.: 05/25/2020
┌tgßfa: 4.0
2.02.03.02.01 Interleukin 2-Rezeptoren

Samheiti: IL-2 Receptors
Hide details for Sřnataka, geymsla og sřnasending Sřnataka, geymsla og sřnasending
Ger­ sřnis : Serum, mŠnuv÷kvi

Sřni teki­ Ý serum glas me­ rau­um tappa me­ geli (gul mi­ja). Litakˇ­i samkvŠmt Greiner

Magn: 1 mL
Geymsla sřnis: Fryst (Frysta sem fyrst)
Sřnasending: Hra­sending ß ■urrÝs
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Kˇ­i: Serum IL2R

MŠnuv÷kvi: ANNAđUT
Bei­ni: 3a hjß Volkmann anforderungsschein_3a.pdfanforderungsschein_3a.pdf
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MVZ Labor PD Dr. Volkmann und Kollegen GbR
Kriegsstrasse 99
76133 Karlsruhe

Tel:á 0721 85000-0
Fax: 0721 85000-199

www.laborvolkmann.de
E-Mail:álabor@laborvolkmann.de

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interleukin-2-rezeptoren.pdfinterleukin-2-rezeptoren.pdf

Frˇ­leikur:
Interleukin-2 Receptor (IL-2R)

Interleukin-2 (IL-2) has been described as a factor that promotes the growth and proliferation of human T-cells thus occupying a pivotal role in the generation of the immune response. This proliferation of T lymphocytes is triggered by the interaction of IL-2 with its specific cell surface receptor following T lymphocyte activation. The receptor for IL-2 is composed of at least three distinct polypeptide subunits , the IL-2R alpha, IL-2R beta, and the IL-2R gamma chains giving rise to a 55-65 kD membrane bound protein. Evidence has accumulated that suggests a critical role of IL-2R beta in IL-2 signal transduction. IL-2R coupled tyrosine kinases are believed to play a crucial role in that signal transduction. In addition to the de-novo expression of IL-2R by activated peripheral blood T-cells, a released and fully soluble form of IL-2R (sIL-2R) has been detected. It was shown that sIL-2R is present in vivo, at low levels in the sera of healthy persons and at markedly elevated levels in various pathological conditions like neoplastic disorders.


Ritstjˇrn

KristÝn Sigurgeirsdˇttir
Sigr˙n H PÚtursdˇttir
Gu­mundur Sig■ˇrsson
Ingibj÷rg Loftsdˇttir

Sam■ykkjendur

┴byrg­arma­ur

═sleifur Ëlafsson

┌tgefandi

Sigr˙n H PÚtursdˇttir

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